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The transient receptor potential channel on the yeast vacuole is mechanosensitive

Ca(2+) is released from the vacuole into the yeast cytoplasm on an osmotic upshock, but how this upshock is perceived was unknown. We found the vacuolar channel, Yvc1p, to be mechanosensitive, showing that the Ca(2+) conduit is also the sensing molecule. Although fragile, the yeast vacuole allows li...

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Detalhes bibliográficos
Main Authors: Zhou, Xin-Liang, Batiza, Ann F., Loukin, Stephen H., Palmer, Chris P., Kung, Ching, Saimi, Yoshiro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165837/
https://ncbi.nlm.nih.gov/pubmed/12771382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1230540100
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