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The transient receptor potential channel on the yeast vacuole is mechanosensitive

Ca(2+) is released from the vacuole into the yeast cytoplasm on an osmotic upshock, but how this upshock is perceived was unknown. We found the vacuolar channel, Yvc1p, to be mechanosensitive, showing that the Ca(2+) conduit is also the sensing molecule. Although fragile, the yeast vacuole allows li...

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Main Authors: Zhou, Xin-Liang, Batiza, Ann F., Loukin, Stephen H., Palmer, Chris P., Kung, Ching, Saimi, Yoshiro
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC165837/
https://ncbi.nlm.nih.gov/pubmed/12771382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1230540100
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