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Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells

A frequent characteristic of human papillomavirus (HPV)-positive cervical cancers is the loss of viral E2 gene expression in HPV-infected cervical epithelial cells as a consequence of viral DNA integration into the cellular genome. The expression of E2 in HPV-positive cancer cells results in the rep...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Wells, Susanne I., Aronow, Bruce J., Wise, Trisha M., Williams, Sarah S., Couget, Jennifer A., Howley, Peter M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165835/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12756294/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1232309100
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