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Toward a detailed computational model for the mammalian circadian clock

We present a computational model for the mammalian circadian clock based on the intertwined positive and negative regulatory loops involving the Per, Cry, Bmal1, Clock, and Rev-Erb α genes. In agreement with experimental observations, the model can give rise to sustained circadian oscillations in co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Leloup, Jean-Christophe, Goldbeter, Albert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC165828/
https://ncbi.nlm.nih.gov/pubmed/12775757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1132112100
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