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Direct observation of photolysis-induced tertiary structural changes in hemoglobin
Human Hb, an α(2)β(2) tetrameric oxygen transport protein that switches from a T (tense) to an R (relaxed) quaternary structure during oxygenation, has long served as a model for studying protein allostery in general. Time-resolved spectroscopic measurements after photodissociation of CO-liganded Hb...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165826/ https://ncbi.nlm.nih.gov/pubmed/12773618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1230629100 |
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