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A role for Z-DNA binding in vaccinia virus pathogenesis

The N-terminal domain of the E3L protein of vaccinia virus has sequence similarity to a family of Z-DNA binding proteins of defined three-dimensional structure and it is necessary for pathogenicity in mice. When other Z-DNA-binding domains are substituted for the similar E3L domain, the virus retain...

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Autors principals: Kim, Yang-Gyun, Muralinath, Maneesha, Brandt, Teresa, Pearcy, Matthew, Hauns, Kevin, Lowenhaupt, Ky, Jacobs, Bertram L., Rich, Alexander
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165815/
https://ncbi.nlm.nih.gov/pubmed/12777633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0431131100
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