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Architecture of initiation-competent 12-subunit RNA polymerase II

RNA polymerase (Pol) II consists of a 10-polypeptide catalytic core and the two-subunit Rpb4/7 complex that is required for transcription initiation. Previous structures of the Pol II core revealed a “clamp,” which binds the DNA template strand via three “switch regions,” and a flexible “linker” to...

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Main Authors: Armache, Karim-Jean, Kettenberger, Hubert, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165813/
https://ncbi.nlm.nih.gov/pubmed/12746495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1030608100
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