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Architecture of initiation-competent 12-subunit RNA polymerase II

RNA polymerase (Pol) II consists of a 10-polypeptide catalytic core and the two-subunit Rpb4/7 complex that is required for transcription initiation. Previous structures of the Pol II core revealed a “clamp,” which binds the DNA template strand via three “switch regions,” and a flexible “linker” to...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Armache, Karim-Jean, Kettenberger, Hubert, Cramer, Patrick
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12746495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1030608100
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