Biochemical Function of msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv: Biosynthesis of Monomethyl Branched Unsaturated Fatty Acids

We show that the disruption of one of the mycocerosic acid synthase (mas)-like genes, msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv generates a mutant incapable of producing monomethyl branched unsaturated C(16) to C(20) fatty acids that are minor constituents of acyltrehaloses and sulf...

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Detalhes bibliográficos
Main Authors: Dubey, Vinod S., Sirakova, Tatiana D., Cynamon, Michael H., Kolattukudy, Pappachan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Physiology and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165776/
https://ncbi.nlm.nih.gov/pubmed/12867474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.15.4620-4625.2003
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