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Biochemical Function of msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv: Biosynthesis of Monomethyl Branched Unsaturated Fatty Acids

We show that the disruption of one of the mycocerosic acid synthase (mas)-like genes, msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv generates a mutant incapable of producing monomethyl branched unsaturated C(16) to C(20) fatty acids that are minor constituents of acyltrehaloses and sulf...

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Udgivet i:J Bacteriol
Principais autores: Dubey, Vinod S., Sirakova, Tatiana D., Cynamon, Michael H., Kolattukudy, Pappachan E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Physiology and Metabolism
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12867474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.15.4620-4625.2003
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