The High-Mobility-Group Box Protein SSRP1/T160 Is Essential for Cell Viability in Day 3.5 Mouse Embryos

The high-mobility-group (HMG) SSRP1 protein is a member of a conserved chromatin-remodeling complex (FACT/DUF/CP) implicated in DNA replication, basal and regulated transcription, and DNA repair. To assist in the functional analysis of SSRP1, the Ssrp1 gene was targeted in murine embryonic stem cell...

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Bibliographic Details
Main Authors: Cao, Shang, Bendall, Heather, Hicks, Geoffrey G., Nashabi, Abudi, Sakano, Hitoshi, Shinkai, Yoichi, Gariglio, Marisa, Oltz, Eugene M., Ruley, H. Earl
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165710/
https://ncbi.nlm.nih.gov/pubmed/12861016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.15.5301-5307.2003
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