Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice

DYRK1A is the human orthologue of the Drosophila minibrain (mnb) gene, which is involved in postembryonic neurogenesis in flies. Because of its mapping position on chromosome 21 and the neurobehavioral alterations shown by mice overexpressing this gene, involvement of DYRK1A in some of the neurologi...

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Detaylı Bibliyografya
Asıl Yazarlar: Fotaki, Vassiliki, Dierssen, Mara, Alcántara, Soledad, Martínez, Salvador, Martí, Eulàlia, Casas, Caty, Visa, Joana, Soriano, Eduardo, Estivill, Xavier, Arbonés, Maria L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC135639/
https://ncbi.nlm.nih.gov/pubmed/12192061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.18.6636-6647.2002
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