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Direct observation of DNA bending/unbending kinetics in complex with DNA-bending protein IHF

Regulation of gene expression involves formation of specific protein–DNA complexes in which the DNA is often bent or sharply kinked. Kinetics measurements of DNA bending when in complex with the protein are essential for understanding the molecular mechanism that leads to precise recognition of spec...

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Библиографические подробности
Главные авторы: Kuznetsov, Serguei V., Sugimura, Sawako, Vivas, Paula, Crothers, Donald M., Ansari, Anjum
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1656971/
https://ncbi.nlm.nih.gov/pubmed/17124171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608394103
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