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Stepwise binding and bending of DNA by Escherichia coli integration host factor

Integration host factor (IHF) is a prokaryotic protein required for the integration of λ phage DNA into its host genome. An x-ray crystal structure of the complex shows that IHF binds to the minor groove of DNA and bends the double helix by 160° [Rice PA, Yang S, Mizuuchi K, Nash HA (1996) Cell 87:1...

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Main Authors: Sugimura, Sawako, Crothers, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1654134/
https://ncbi.nlm.nih.gov/pubmed/17116862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608337103
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