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Direct observation of DNA bending/unbending kinetics in complex with DNA-bending protein IHF

Regulation of gene expression involves formation of specific protein–DNA complexes in which the DNA is often bent or sharply kinked. Kinetics measurements of DNA bending when in complex with the protein are essential for understanding the molecular mechanism that leads to precise recognition of spec...

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Detalhes bibliográficos
Main Authors: Kuznetsov, Serguei V., Sugimura, Sawako, Vivas, Paula, Crothers, Donald M., Ansari, Anjum
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1656971/
https://ncbi.nlm.nih.gov/pubmed/17124171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608394103
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