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A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation

Nuclear receptor corepressors SMRT (silencing mediator of retinoid and thyroid receptors) and N-CoR (nuclear receptor corepressor) recruit histone deacetylase (HDAC) activity to targeted regions of chromatin. These corepressors contain a closely spaced pair of SANT motifs whose sequence and organiza...

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Detalhes bibliográficos
Main Authors: Yu, Jiujiu, Li, Yun, Ishizuka, Takahiro, Guenther, Matthew G., Lazar, Mitchell A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165650/
https://ncbi.nlm.nih.gov/pubmed/12840002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg326
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