G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells

We studied the function of G protein-coupled receptor kinases (GRKs) in the regulation of thrombin-activated signaling in endothelial cells. GRK2, GRK5, and GRK6 isoforms were expressed predominantly in endothelial cells. The function of these isoforms was studied by expressing wild-type and dominan...

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Autores principales: Tiruppathi, Chinnaswamy, Yan, Weihong, Sandoval, Raudel, Naqvi, Tabassum, Pronin, Alexey N., Benovic, Jeffery L., Malik, Asrar B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC16564/
https://ncbi.nlm.nih.gov/pubmed/10861009
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