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JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun

The AP-1 transcription factor c-Jun is a prototypical nuclear effector of the JNK signal transduction pathway. The integrity of JNK phosphorylation sites at serines 63/73 and at threonines 91/93 in c-Jun is essential for signal-dependent target gene activation. We show that c-Jun phosphorylation med...

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Bibliografiske detaljer
Main Authors: Weiss, Carsten, Schneider, Sandra, Wagner, Erwin F., Zhang, Xiaohong, Seto, Edward, Bohmann, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165634/
https://ncbi.nlm.nih.gov/pubmed/12853483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg364
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