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The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase

The Cdc14 family of dual-specificity protein phosphatases (DSPs) is conserved within eukaryotes and functions to down-regulate mitotic Cdk activities, promoting cytokinesis and mitotic exit. We have integrated structural and kinetic analyses to define the molecular mechanism of the dephosphorylation...

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Detalhes bibliográficos
Main Authors: Gray, Christopher H., Good, Valerie M., Tonks, Nicholas K., Barford, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165618/
https://ncbi.nlm.nih.gov/pubmed/12853468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg348
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