Chromosome instability contributes to loss of heterozygosity in mice lacking p53

The p53 tumor suppressor protein participates in multiple cellular processes including cell cycle checkpoints and programmed cell death. In cell lines, loss of p53 function is associated with increased genetic instability including aneuploidy, gene amplification, and point mutation. Although similar...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Shao, Changshun, Deng, Li, Henegariu, Octavian, Liang, Li, Stambrook, Peter J., Tischfield, Jay A.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10861008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.13.7405
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