High accuracy genotyping directly from genomic DNA using a rolling circle amplification based assay

BACKGROUND: Rolling circle amplification of ligated probes is a simple and sensitive means for genotyping directly from genomic DNA. SNPs and mutations are interrogated with open circle probes (OCP) that can be circularized by DNA ligase when the probe matches the genotype. An amplified detection si...

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Bibliografski detalji
Glavni autori: Alsmadi, Osama A, Bornarth, Carole J, Song, Wanmin, Wisniewski, Michele, Du, Jing, Brockman, Joel P, Faruqi, A Fawad, Hosono, Seiyu, Sun, Zhenyu, Du, Yuefen, Wu, Xiaohong, Egholm, Michael, Abarzúa, Patricio, Lasken, Roger S, Driscoll, Mark D
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2003
Teme:
Methodology Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC165428/
https://ncbi.nlm.nih.gov/pubmed/12777185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-4-21
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