High accuracy genotyping directly from genomic DNA using a rolling circle amplification based assay

BACKGROUND: Rolling circle amplification of ligated probes is a simple and sensitive means for genotyping directly from genomic DNA. SNPs and mutations are interrogated with open circle probes (OCP) that can be circularized by DNA ligase when the probe matches the genotype. An amplified detection si...

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Detalhes bibliográficos

Publicado no:	BMC Genomics
Principais autores:	Alsmadi, Osama A, Bornarth, Carole J, Song, Wanmin, Wisniewski, Michele, Du, Jing, Brockman, Joel P, Faruqi, A Fawad, Hosono, Seiyu, Sun, Zhenyu, Du, Yuefen, Wu, Xiaohong, Egholm, Michael, Abarzúa, Patricio, Lasken, Roger S, Driscoll, Mark D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2003
Assuntos:	Methodology Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12777185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-4-21
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