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High accuracy genotyping directly from genomic DNA using a rolling circle amplification based assay
BACKGROUND: Rolling circle amplification of ligated probes is a simple and sensitive means for genotyping directly from genomic DNA. SNPs and mutations are interrogated with open circle probes (OCP) that can be circularized by DNA ligase when the probe matches the genotype. An amplified detection si...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165428/ https://ncbi.nlm.nih.gov/pubmed/12777185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-4-21 |
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