Cholesterol Depletion of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus with β-Cyclodextrin Inactivates and Permeabilizes the Virions: Evidence for Virion-Associated Lipid Rafts

Recent evidence suggests that human immunodeficiency virus type 1 (HIV-1) particles assemble and bud selectively through areas in the plasma membrane of cells that are highly enriched with glycosylphosphatidylinositol-anchored proteins and cholesterol, called lipid rafts. Since cholesterol is requir...

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Pubblicato in:	J Virol
Autori principali:	Graham, David R. M., Chertova, Elena, Hilburn, Joanne M., Arthur, Larry O., Hildreth, James E. K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Structure and Assembly
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.15.8237-8248.2003
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