Cholesterol Depletion of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus with β-Cyclodextrin Inactivates and Permeabilizes the Virions: Evidence for Virion-Associated Lipid Rafts

Recent evidence suggests that human immunodeficiency virus type 1 (HIV-1) particles assemble and bud selectively through areas in the plasma membrane of cells that are highly enriched with glycosylphosphatidylinositol-anchored proteins and cholesterol, called lipid rafts. Since cholesterol is requir...

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Detalhes bibliográficos
Main Authors: Graham, David R. M., Chertova, Elena, Hilburn, Joanne M., Arthur, Larry O., Hildreth, James E. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165256/
https://ncbi.nlm.nih.gov/pubmed/12857892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8237-8248.2003
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