A Naturally Occurring Substitution in Human Immunodeficiency Virus Tat Increases Expression of the Viral Genome

A natural amino acid substitution in the human immunodeficiency virus type 1 (HIV-1) transcriptional activator Tat increases its activity and compensates for deleterious mutations elsewhere in the Tat protein. Substitution of asparagine for threonine 23 increases Tat transactivation of the HIV-1 pro...

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Main Authors: Reza, Syed M., Shen, Lin-Ming, Mukhopadhyay, Rupa, Rosetti, Mihaela, Pe'ery, Tsafi, Mathews, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165250/
https://ncbi.nlm.nih.gov/pubmed/12857933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8602-8606.2003
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