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Centrosomes Split in the Presence of Impaired DNA Integrity during Mitosis

A well-established function of centrosomes is their role in accomplishing a successful mitosis that gives rise to a pair of identical daughter cells. We recently showed that DNA replication defects and DNA damage in Drosophila embryos trigger centrosomal changes, but it remained unclear whether comp...

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Detalhes bibliográficos
Main Authors: Hut, Henderika M.J., Lemstra, Willy, Blaauw, Engbert H., van Cappellen, Gert W.A., Kampinga, Harm H., Sibon, Ody C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165092/
https://ncbi.nlm.nih.gov/pubmed/12802070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0510
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