Perlecan Up-Regulation of FRNK Suppresses Smooth Muscle Cell Proliferation via Inhibition of FAK Signaling

We previously reported that fully assembled basement membranes are nonpermissive to smooth muscle cell (SMC) replication and that perlecan (PN), a basement membrane heparan sulfate proteoglycan, is a dominant effector of this response. We report here that SMC adhesion to basement membranes, and perl...

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Detalhes bibliográficos
Main Authors: Walker, Heather A., Whitelock, John M., Garl, Pamela J., Nemenoff, Raphael A., Stenmark, Kurt R., Weiser-Evans, Mary C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165088/
https://ncbi.nlm.nih.gov/pubmed/12802066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0508
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