Perlecan Up-Regulation of FRNK Suppresses Smooth Muscle Cell Proliferation via Inhibition of FAK Signaling

We previously reported that fully assembled basement membranes are nonpermissive to smooth muscle cell (SMC) replication and that perlecan (PN), a basement membrane heparan sulfate proteoglycan, is a dominant effector of this response. We report here that SMC adhesion to basement membranes, and perl...

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Autori principali: Walker, Heather A., Whitelock, John M., Garl, Pamela J., Nemenoff, Raphael A., Stenmark, Kurt R., Weiser-Evans, Mary C.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2003
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC165088/
https://ncbi.nlm.nih.gov/pubmed/12802066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0508
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