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Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees

To examine the effect of transforming growth factor (TGF)-β1 on the regulation of cartilage synthesis and other articular pathologies, we used adenovirus-mediated intra-articular gene transfer of TGF-β1 to both naïve and arthritic rabbit knee joints. Increasing doses of adenoviral vector expressing...

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Bibliografische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Mi, Zhibao, Ghivizzani, Steven C, Lechman, Eric, Glorioso, Joseph C, Evans, Christopher H, Robbins, Paul D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12723985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar745
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