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Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees

To examine the effect of transforming growth factor (TGF)-β1 on the regulation of cartilage synthesis and other articular pathologies, we used adenovirus-mediated intra-articular gene transfer of TGF-β1 to both naïve and arthritic rabbit knee joints. Increasing doses of adenoviral vector expressing...

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Detalhes bibliográficos
Main Authors: Mi, Zhibao, Ghivizzani, Steven C, Lechman, Eric, Glorioso, Joseph C, Evans, Christopher H, Robbins, Paul D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165041/
https://ncbi.nlm.nih.gov/pubmed/12723985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar745
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