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Mycobacterium tuberculosis Chaperonin 10 Heptamers Self-Associate through Their Biologically Active Loops

The crystal structure of Mycobacterium tuberculosis chaperonin 10 (cpn10(Mt)) has been determined to a resolution of 2.8 Å. Two dome-shaped cpn10(Mt) heptamers complex through loops at their bases to form a tetradecamer with 72 symmetry and a spherical cage-like structure. The hollow interior enclos...

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Autors principals: Roberts, Michael M., Coker, Alun R., Fossati, Gianluca, Mascagni, Paolo, Coates, Anthony R. M., Wood, Steve P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164875/
https://ncbi.nlm.nih.gov/pubmed/12837792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4172-4185.2003
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