Nrf1 Is Critical for Redox Balance and Survival of Liver Cells during Development

The Nrf1 transcription factor belongs to the CNC subfamily of basic leucine zipper proteins. Knockout of Nrf1 is lethal in mouse embryos, but nothing is known about the cell types that absolutely require its function during development. We show by chimera analysis that Nrf1 is essential for the hepa...

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Detalhes bibliográficos
Main Authors: Chen, Linyun, Kwong, Mandy, Lu, Ronghua, Ginzinger, David, Lee, Candy, Leung, Laura, Chan, Jefferson Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164851/
https://ncbi.nlm.nih.gov/pubmed/12808106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4673-4686.2003
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