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Sulfiredoxin Protein Is Critical for Redox Balance and Survival of Cells Exposed to Low Steady-state Levels of H(2)O(2)

Sulfiredoxin (Srx) is an enzyme that catalyzes the reduction of cysteine sulfinic acid of hyperoxidized peroxiredoxins (Prxs). Having high affinity toward H(2)O(2), 2-Cys Prxs can efficiently reduce H(2)O(2) at low concentration. We previously showed that Prx I is hyperoxidized at a rate of 0.072% p...

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Detaylı Bibliyografya
Asıl Yazarlar: Baek, Jin Young, Han, Sun Hee, Sung, Su Haeng, Lee, Hye Eun, Kim, Yu-mi, Noh, You Hyun, Bae, Soo Han, Rhee, Sue Goo, Chang, Tong-Shin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249139/
https://ncbi.nlm.nih.gov/pubmed/22086924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.316711
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