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Selectable System for Monitoring the Instability of CTG/CAG Triplet Repeats in Mammalian Cells
Despite substantial progress in understanding the mechanism by which expanded CTG/CAG trinucleotide repeats cause neurodegenerative diseases, little is known about the basis for repeat instability itself. By taking advantage of a novel phenomenon, we have developed a selectable assay to detect contr...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164839/ https://ncbi.nlm.nih.gov/pubmed/12808091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4485-4493.2003 |
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