Selectable System for Monitoring the Instability of CTG/CAG Triplet Repeats in Mammalian Cells

Despite substantial progress in understanding the mechanism by which expanded CTG/CAG trinucleotide repeats cause neurodegenerative diseases, little is known about the basis for repeat instability itself. By taking advantage of a novel phenomenon, we have developed a selectable assay to detect contr...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Gorbunova, Vera, Seluanov, Andrei, Dion, Vincent, Sandor, Zoltan, Meservy, James L., Wilson, John H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2003
Fag:	DNA Dynamics and Chromosome Structure
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164839/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4485-4493.2003
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