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Yeast-Based Genetic System for Functional Analysis of Poxvirus mRNA Cap Methyltransferase

Structural differences between poxvirus and human mRNA capping enzymes recommend cap formation as a target for antipoxviral drug discovery. Genetic and pharmacologic analysis of the poxvirus capping enzymes requires in vivo assays in which the readout depends on the capacity of the viral enzyme to c...

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Bibliografische gegevens
Hoofdauteurs: Saha, Nayanendu, Shuman, Stewart, Schwer, Beate
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164803/
https://ncbi.nlm.nih.gov/pubmed/12805428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7300-7307.2003
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