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Yeast-Based Genetic System for Functional Analysis of Poxvirus mRNA Cap Methyltransferase

Structural differences between poxvirus and human mRNA capping enzymes recommend cap formation as a target for antipoxviral drug discovery. Genetic and pharmacologic analysis of the poxvirus capping enzymes requires in vivo assays in which the readout depends on the capacity of the viral enzyme to c...

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Detalhes bibliográficos
Main Authors: Saha, Nayanendu, Shuman, Stewart, Schwer, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164803/
https://ncbi.nlm.nih.gov/pubmed/12805428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7300-7307.2003
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