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Yeast-Based Genetic System for Functional Analysis of Poxvirus mRNA Cap Methyltransferase

Structural differences between poxvirus and human mRNA capping enzymes recommend cap formation as a target for antipoxviral drug discovery. Genetic and pharmacologic analysis of the poxvirus capping enzymes requires in vivo assays in which the readout depends on the capacity of the viral enzyme to c...

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Bibliografske podrobnosti
Main Authors: Saha, Nayanendu, Shuman, Stewart, Schwer, Beate
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC164803/
https://ncbi.nlm.nih.gov/pubmed/12805428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7300-7307.2003
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