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Yeast-Based Genetic System for Functional Analysis of Poxvirus mRNA Cap Methyltransferase
Structural differences between poxvirus and human mRNA capping enzymes recommend cap formation as a target for antipoxviral drug discovery. Genetic and pharmacologic analysis of the poxvirus capping enzymes requires in vivo assays in which the readout depends on the capacity of the viral enzyme to c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164803/ https://ncbi.nlm.nih.gov/pubmed/12805428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7300-7307.2003 |
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