Viability of Poliovirus/Rhinovirus VPg Chimeric Viruses and Identification of an Amino Acid Residue in the VPg Gene Critical for Viral RNA Replication

Picornaviral RNA replication utilizes a small virus-encoded protein, termed 3B or VPg, as a primer to initiate RNA synthesis. This priming step requires uridylylation of the VPg peptide by the viral polymerase protein 3D(pol), in conjunction with other viral or host cofactors. In this study, we comp...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Cheney, I. Wayne, Naim, Suhaila, Shim, Jae Hoon, Reinhardt, Meghan, Pai, Bharati, Wu, Jim Z., Hong, Zhi, Zhong, Weidong
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2003
Matèries:	Replication
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7434-7443.2003
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