Viability of Poliovirus/Rhinovirus VPg Chimeric Viruses and Identification of an Amino Acid Residue in the VPg Gene Critical for Viral RNA Replication

Picornaviral RNA replication utilizes a small virus-encoded protein, termed 3B or VPg, as a primer to initiate RNA synthesis. This priming step requires uridylylation of the VPg peptide by the viral polymerase protein 3D(pol), in conjunction with other viral or host cofactors. In this study, we comp...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Cheney, I. Wayne, Naim, Suhaila, Shim, Jae Hoon, Reinhardt, Meghan, Pai, Bharati, Wu, Jim Z., Hong, Zhi, Zhong, Weidong
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Replication
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7434-7443.2003
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