Human Gene Targeting by Adeno-Associated Virus Vectors Is Enhanced by DNA Double-Strand Breaks
The use of adeno-associated virus (AAV) to package gene-targeting vectors as single-stranded linear molecules has led to significant improvements in mammalian gene-targeting frequencies. However, the molecular basis for the high targeting frequencies obtained is poorly understood, and there could be...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12724413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.10.3550-3557.2003 |
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