Caspase 8 small interfering RNA prevents acute liver failure in mice

A major concern in therapy of acute liver failure is protection of hepatocytes to prevent apoptosis and maintain liver function. Small interfering RNA (siRNA) is a powerful tool to silence gene expression in mammalian cells. To evaluate the therapeutic efficacy of siRNA in vivo we used different mou...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Zender, Lars, Hütker, Sebastian, Liedtke, Christian, Tillmann, Hans Ludger, Zender, Steffen, Mundt, Bettina, Waltemathe, Morlen, Gösling, Thomas, Flemming, Peer, Malek, Nisar Peter, Trautwein, Christian, Manns, Michael Peter, Kühnel, Florian, Kubicka, Stefan
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12810955/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1330920100
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