Differential proteasomal processing of hydrophobic and hydrophilic protein regions: Contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef

HIV proteins contain a multitude of naturally processed cytotoxic T lymphocyte (CTL) epitopes that concentrate in clusters. The molecular basis of epitope clustering is of interest for understanding HIV immunogenicity and for vaccine design. We show that the CTL epitope clusters of HIV proteins pred...

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Bibliografiset tiedot
Päätekijät: Lucchiari-Hartz, Maria, Lindo, Viv, Hitziger, Niclas, Gaedicke, Simone, Saveanu, Loredana, van Endert, Peter M., Greer, Fiona, Eichmann, Klaus, Niedermann, Gabriele
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC164660/
https://ncbi.nlm.nih.gov/pubmed/12810958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232228100
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