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Fast gating in the Shaker K(+) channel and the energy landscape of activation

An early component of the gating current in Shaker K(+) channels with a time constant of ≈12 μsec has been recorded with a high-speed patch–clamp setup. This fast component was found to be part of the gating current associated with the opening and closing of the channel. With regard to an energy-lan...

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Autori principali: Sigg, Daniel, Bezanilla, Francisco, Stefani, Enrico
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164634/
https://ncbi.nlm.nih.gov/pubmed/12805566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332409100
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