Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation

Heterochromatin formation in yeast involves deacetylation of histones, but the precise relationship between acetylation and the association of proteins such as Sir3, Sir4, and the histone deacetylase Sir2 with chromatin is still unclear. Here we show that Sir3 protein spreads to subtelomeric DNA in...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Kristjuhan, Arnold, Wittschieben, Birgitte Ø., Walker, Jane, Roberts, Douglas, Cairns, Bradley R., Svejstrup, Jesper Q.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12796514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1332299100
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