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Direct molecular haplotyping of long-range genomic DNA with M1-PCR

Haplotypes, combinations of several phase-determined polymorphic markers, are extremely valuable for studies of disease association and chromosome evolution. Here we describe a technique called M1-PCR (M for ``multiplex'' and 1 for ``single-copy DNA molecules'') that enables dire...

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Detalhes bibliográficos
Main Authors: Ding, Chunming, Cantor, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164606/
https://ncbi.nlm.nih.gov/pubmed/12802015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232475100
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