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Guanylate cyclase-activating protein (GCAP) 1 rescues cone recovery kinetics in GCAP1/GCAP2 knockout mice
Mediated by guanylate cyclase-activating proteins (GCAPs), cytoplasmic Ca(2+) levels regulate the activity of photoreceptor guanylate cyclase (GC) and the synthesis of cGMP, the internal transmitter of phototransduction. When GCAP1 is expressed in transgenic mice on a GCAP null background, it restor...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164524/ https://ncbi.nlm.nih.gov/pubmed/12732716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1130102100 |
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