An EP2 receptor-selective prostaglandin E(2) agonist induces bone healing

The morbidity and mortality associated with impaired/delayed fracture healing remain high. Our objective was to identify a small nonpeptidyl molecule with the ability to promote fracture healing and prevent malunions. Prostaglandin E(2) (PGE(2)) causes significant increases in bone mass and bone str...

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Bibliographische Detailangaben
Hauptverfasser: Paralkar, V. M., Borovecki, F., Ke, H. Z., Cameron, K. O., Lefker, B., Grasser, W. A., Owen, T. A., Li, M., DaSilva-Jardine, P., Zhou, M., Dunn, R. L., Dumont, F., Korsmeyer, R., Krasney, P., Brown, T. A., Plowchalk, D., Vukicevic, S., Thompson, D. D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164516/
https://ncbi.nlm.nih.gov/pubmed/12748385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1037343100
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