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Beta cell MHC class I is a late requirement for diabetes
Type 1 diabetes occurs as a result of an autoimmune attack on the insulin-producing beta cells. Although CD8 T cells have been implicated both early and late in this process, the requirement for direct interaction between these cells and MHC class I on the beta cells has not been demonstrated. By us...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164508/ https://ncbi.nlm.nih.gov/pubmed/12750472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1131954100 |
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