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MHC class I pathway is not required for the development of crescentic glomerulonephritis in mice

MHC II and CD4(+) T cells are required for anti-glomerular basement membrane (GBM) globulin-initiated crescentic glomerulonephritis (GN) in mice, but the role of MHC I and CD8(+) T cells is unclear. The cytolytic function of CD8(+) T cells requires recognition of peptide antigens presented on MHC I....

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Detalhes bibliográficos
Main Authors: Li, S, Holdsworth, S R, Tipping, P G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905810/
https://ncbi.nlm.nih.gov/pubmed/11122254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01387.x
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